Vape Puffs vs. Cigarettes: How Many Equal One? Guide to E Cigarettes: Vaping vs. Smoking, How to Choose, Tips Vape to Cigarette Conversion: How Many Cigarettes Equal Your Vape Hits Velvet Cloud Vapes and E Cigs Alabama Department of Public Health (ADPH) The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking Doctor says smoking one vape is equivalent of disturbing amount of cigarettes