Viscosupplementation injections for knee pain relief The Role of Lubricin, Irisin and Exercise in the Prevention and Treatment of Osteoarthritis Hyaluronic acid injections are designed to support joint lubrication and improve knee functionhelping to ease symptoms in some people with knee osteoarthritis. They work best as part of a bigger plan, How Do Cartilage Lubrication Mechanisms Fail in Osteoarthritis? A Comprehensive Review A gel injection for the knee helps improve joint lubrication when natural synovial fluid becomes thinner or less effective, which often happens with arthritis., This gel acts as a cushion and Viscosupplementation: How Gel Injections Restore Your Knee's Natural Cushioning Joint Relief Institute